DanDi Bioscience

Superbacteria Infection Therapy

In order to modulate excessive immune responses initiated by endotoxins released upon the death of gram-negative bacteria following antibiotic treatment, our research department has recently discovered a unique antibiotic candidate named "DD-S052P"

“DD-S052” is similar to Polymyxin B in its mode of action, without its excessive toxicity. “DD-S052P” is capable of directly killing the bacteria and simultaneously binding to the endotoxins released as a byproduct of the elimination process.

With its low toxicity and potent mode of action, "DD-S052P" is a promising candidate in the treatment of endotoxin-releasing gram negative bacterial infections and multidrug-resistant superbacteria infections, both of which are serious public health issues.

Development history and scalability using Dfpep-based technology